FAQ: Is live SARS-CoV-2 virus inactivated during extraction with the Monarch Total RNA Miniprep Kit?

Though NEB has not internally validated viral inactivation using the Monarch Total RNA Miniprep Kit, users of our products have confirmed that both the Monarch RNA Lysis Buffer (NEB #T2012) and Monarch DNA/RNA Protection Reagent (NEB #T2011) are effective in inactivating the live SARS-CoV-2 virus under certain conditions. Monarch kits are sold for research use only (RUO) and users should always adhere to the safety guidelines of their institution.