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Using large-scale RNA sequencing to probe immune response, including autoimmune disease and vaccination
Posted on Wednesday, October 13, 2021 By
Researchers are efficiently exploring immune responses with a new bulk RNA sequencing workflow that generates full-length reads of B or T cell receptor V(D)J and (C) region mRNA. The discoveries incorporating this unique view are shedding light on previously unanswerable questions surrounding immune response to infection and therapeutic intervention.
8 tips to follow when choosing a restriction enzyme for in vitro mRNA vaccine production
Posted on Friday, September 24, 2021 By
mRNA vaccines have emerged as alternatives to conventional vaccine approaches because of the streamlined path from early discovery and development to a point-of-care therapeutic. In this post, read practical tips to consider when choosing a restriction enzyme for one of the crucial first steps of IVT vaccine development - linearizing the plasmid that contains the vaccine target sequence.
Bioinformatics alerts for viral variant impacts on molecular tests
Posted on Wednesday, August 11, 2021 By
NEB bioinformatics scientist Brad Langhorst, Ph.D., discusses the impact of emerging variants on existing SARS-CoV-2 molecular tests, the key factor in test failures, who benefits from using NEB's new, Primer Monitor tool, and lessons from the pandemic for infectious disease outbreaks.
5 Tips to Stand out on LinkedIn with a Great Scientist Profile
Posted on Wednesday, June 30, 2021 By
Life science recruiters and hiring managers frequently use LinkedIn to find job candidates. We spoke to a LinkedIn expert to explore how to make your LinkedIn profile help you find the perfect job in science.
RT-qPCR strategies for molecular diagnostics, OEM and customized solutions
Posted on Thursday, June 24, 2021 By
NEB Scientist Greg Patton, Ph.D., discusses how the molecular diagnostics field improves assay accuracy, robustness, and accessibility, for COVID RT-qPCR testing - including molecular technical advantages, OEM and customized reagent considerations to put upfront, and a tool to monitor for viral variant effects.
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