
Epigenetics
Choose Type:
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Epigenetics - Expanding on Genomic Foundations
- Epigenetics Brochure
- EpiMark® Methylated DNA Enrichment Kit Troubleshooting Guide
- EM-seq™ Enables Accurate and Precise Methylome Analysis of Challenging DNA Samples (2019)
- EM-seq™ enables accurate and robust methylation detection of cell free DNA and FFPE DNA sample types
- Enzymatic Methyl-seq: Next Generation Methylomes (2019)
- NicE-seq: High Resolution Open Chromatin Profiling (2018)
- Small RNA-Mediated DNA Methyltransferase 1 Inhibition Causes DNA Methylation Alteration in Mammalian Cells (2015)
- Uncovering the Cannabis sativa Methylome Through Enzymatic Methyl-seq (2019)
Feature Articles
Brochures
Troubleshooting Guides
Posters
- Wanunu, M. et al. 2010. Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecular J. Am. Chem. Soc.. 133(3), PubMedID: 21155562, DOI:
- Laget, S., et al. 2010. The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA PLoS One. 5, PubMedID: 20700456, DOI:
- Wanunu, M., et al. 2010. Rapid electronic detection of probe-specific microRNAs using thin nanopore sensors Nature Nanotech. 5, PubMedID: 20972437, DOI:
- Zheng, Y. et al. 2010. A unique family of Mrr-like modification-dependent restriction endonucleases Nucl. Acids Res.. 38(16), PubMedID: 20444879, DOI:
- Jensen, H.M., et al. 2010. Engineering of a synthetic electron conduit in living cells Proc. Natl. Acad. Sci. USA. 107, PubMedID: 20956333, DOI:
- Sexton T, Kurukuti S, Mitchell JA, Umlauf D, Nagano T, Fraser P 2012. Sensitive detection of chromatin coassociations using enhanced chromosome conformation capture on chip Nat Protoc. 7(7), PubMedID: 22722369, DOI: 10.1038/nprot.2012.071
- Ho, J.J., et al. 2012. Functional importance of Dicer protein in the adaptive cellular response to hypoxia J. Biol. Chem.. 17, PubMedID: 22745131, DOI: 10.174/jbcM112.373365
- Grant, T.J., et al. 2012. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma Proc. Natl. Acad. Sci. USA. 109, PubMedID: 22396589, DOI:
- Foraker, A.B., et al. 2012. Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG J. Cell Bio.. 198, PubMedID: , DOI:
- Gu, L.Q., et al. 2012. Detection of miRNAs with a nanopore single-molecule counter Expert Rev. Mol. Diagn.. 12, PubMedID: 22845478, DOI:
- Gong, H. wt al. 2012. Near-infrared fluorescence imaging of mammalian cells and xenograft tumors with SNAP-tag PLoS ONE. 7, PubMedID: 22479502, DOI:
- Chernov AV., Reyes L., Peterson S., Strongin AY. 2015. Depletion of CG-Specific Methylation in Mycoplasma hyorhinis Genomic DNA after Host Cell Invasion PLoS One. 10, PubMedID: 26544880, DOI: 10.1371/journal.pone.0142529
- Kienhöfer S., Musheev M., Stapf U., Helm M., Schomacher L., Niehrs C., Schäfer A. 2015. GADD45a physically and functionally interacts with TET1Publication Differentiation. , PubMedID: 26546041, DOI: 10.1016/j.diff.2015.10.003
- Page A., Paoli P., Salvador E., White S., French J., Mann J. 2015. Hepatic Stellate Cell Transdifferentiation Involves Genome-Wide Remodeling of the DNA Methylation Landscape J Hepatol. , PubMedID: 26632634, DOI: 10.1016/j.jhep.2015.11.024
- Wee E., Ngo T., Trau M. 2015. A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation Sci Rep. 5, PubMedID: 26458746, DOI: 10.1038/srep15028
- Diep, D. and Zhang, K. 2011. Genome-wide mapping of the sixth base Genome Biol. . 12, PubMedID: 21682934, DOI: 10.1186/gb-2010-12-6-116
- Nelson, F.K, Snyder, M., Gardner, A.F., Hendrickson, C.L., Shendure, J.A., Porreca, G.J., Church, G.M., Ausubel, F.M., Ju, J., Kieleczawa, J. and Slatko, B.E 2011. Introduction and historical overview of DNA sequencing <em>Curr. Prot. Mol. Biol</em>. Unit 7.0.1-7.0.18., PubMedID: , DOI:
- Wolff, E.M. et al. 2011. Hypomethylation of a LINE-1 Promoter Activates an Alternate Transcript of the MET Oncogene in Bladders with Cancer PLoS Genet. . 6, PubMedID: 20421991, DOI:
- Kinney, S.M. et al. 2011. Tissue specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genome J. Biol. Chem. . , PubMedID: 21610077, DOI:
- Cohen-Karni, D, et al. 2011. The MspJI family of modification-dependent restriction endonucleases for epigenetic studies Proc. Natl. Acad. Sci. . , PubMedID: 21690366, DOI: 10.1073/pnas.1018448108
- Stroud, H., et al. 2011. 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells Gen. Biol.. , PubMedID: 21689397 , DOI:
- Canc. Res. 2011. 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1 . 71, PubMedID: 21239472, DOI:
- Ficz, G., et al. 2011. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation Nature . , PubMedID: 21460836, DOI: 10.1038/nature10008
- Zhang, J. et al. 2011. Cyclophosphamide perturbs cytosine methylation in jurkat-T Cells through LSD1-mediated stabilization of DNMT1 Protein Chem. Res. Toxicol.. 24(11), PubMedID: 22007908, DOI:
- 2011. Comparitive characterization of the PvuRts11 family and application in mapping genomic 5-hydroxymethylcytosine Nucl. Acids Res.. 39, PubMedID: 21813453, DOI: 10.1093/nar/gkr607
- Marx V. 2016. Genetics: profiling DNA methylation and beyond Nature Methods. 13, PubMedID: , DOI: 10.1038/nmeth.3736
- Mooijman D, Dey S S, Boisset JC, Crosetto N, van Oudenaarden A 2016. Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction Nature Biotechnology. 34, PubMedID: 27347753, DOI: 10.1038/nbt.3598
Amino Acid | Modification |
---|---|
Lysine | Methylation, Acetylation, Ubiquitination, Sumoylation, ADP-Ribosylation |
Arginine | Methylation |
Serine | Phosphorylation |
Threonine | Phosphorylation |

References
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- Kriaucionis, S. and Heintz, N. (2009) Science 324, 929-930. PMID: 19372393
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- Ehrlich, M., Wilson, G.G., Kuo, K.C., And Gehrke, C.W. (1987) J. Bacteriol. 169, 939-943. PMID: 3029036
- Svadbina, I.V., Zelinskaya, N.V., Kovalevskaya, N.P., Zheleznaya, L.A. and Matvienko, N.I. (2004) Biochem. (Moscow) 69, 299-305. PMID: 15061697
- Ratel, D., Ravanat, J-L., Berger, F. and Wion D. (2006) Bioessays 28, 309-315. PMID: 16479578
- Marinus, M.G. and Casadesus, J. (2009) FEMS Microbiol. Rev. 33, 488-503. PMID: 19175412
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