cloned at NEB recombinant engineered time saver neb31 dil_A 37 No

We are excited to announce that we are in the process of switching all reaction buffers to be BSA-free. Beginning April 2021, we will be gradually transitioning to buffers containing Recombinant Albumin (rAlbumin) for restriction enzymes and some DNA modifying enzymes. All information on the website has been updated to reflect this change. Find more details at

NEB high fidelity restriction endonuclease that recognizes the sequence G^GATC_C

Not sensitive to dam, dcm or mammalian CpG methylation.

High-Fidelity (HF®) restriction enzymes have the same specificity as native enzymes, but have been engineered for significantly reduced star activity and performance in a single buffer (rCutSmart Buffer).  All HF-restriction enzymes come with Gel Loading Dye, Purple (6X).  Enjoy the enhanced performance and added value of our engineered enzymes at the same price as the native enzyme:

  • Engineered for improved performance
  • 100% activity in rCutSmart Buffer
  • Time-Saver™ qualified for digestion in 5-15 minutes
  • Reduced star activity
  • Supplied with 1 vial of Gel Loading Dye, Purple (6X)
  • Cut Site: G/GATCC
Catalog # Concentration Size List Price Your Price Quantity
R3136S 20,000 units/ml 10,000 units $111.60
R3136T 100,000 units/ml 10,000 units $111.60
R3136L 20,000 units/ml 50,000 units $457.20
R3136M 100,000 units/ml 50,000 units $457.20
Please enter a quantity for at least one size
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